Which cytotoxic lymphocyte granules contain serine proteases that induce apoptosis in target cells?.
A. Perforins.
B. Cytokines.
C. Granzymes.
D. Interferons.
Granzymes.
Granzymes are a family of serine proteases that are stored in and secreted from the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
They work in synergy with perforin, a pore-forming toxin, to induce apoptosis in target cells.
Perforin is necessary for the delivery of granzyme B to the target cell cytosol where caspase-dependent and -independent pathways to apoptosis are activated.
Perforins (choice A) are pore-forming toxins that work in synergy with granzymes to induce apoptosis in target cells.
Cytokines (choice B) are signaling molecules that regulate immune responses but do not directly induce apoptosis in target cells.
Interferons (choice D) are a type of cytokine that play a role in immune responses but do not directly induce apoptosis in target cells.
Therefore, the Correct Answer is C.
More Questions on TEAS 7 Science
-
Q #1: Which subatomic particle contributes to the positive charge of an atom?
A. Proton
B. Neutron
C. Electron
D. Nucleon
Answer Explanation
Protons contribute to the positive charge of an atom.
Protons are subatomic particles with a positive charge found in the nucleus of an atom.
Choice B is incorrect because neutrons are neutral and do not have a charge. Choice C is incorrect because electrons have a negative charge.
Choice D is incorrect because nucleons refer to both protons and neutrons, but only protons contribute to the positive charge of an atom.
-
Q #2: A nurse is conducting a research study to compare the effects of two different pain medications on postoperative patients. The nurse randomly assigns the patients to either receive medication A or medication B. Which of the following is the best way to ensure that the study is valid and reliable?
A. Use a large sample size and a standardized procedure for administering the medications.
B. Use a placebo group and a double-blind technique for giving the medications.
C. Use a matched-pairs design and a crossover technique for switching the medications.
D. Use a convenience sample and a pretest-posttest design for measuring the pain levels.
Answer Explanation
The correct answer is choice B.
Using a placebo group and a double-blind technique for giving the medications is the best way to ensure that the study is valid and reliable.
A placebo group helps control for the placebo effect, which can influence the results of a study.
A double-blind technique means that neither the patients nor the researchers know which medication is being given, reducing bias.
Choice A is not the best answer because while a large sample size and standardized procedure can increase reliability, they do not address validity.
Choice C is not the best answer because a matched-pairs design and crossover technique are useful for reducing variability but do not address validity.
Choice D is not the best answer because a convenience sample may not be representative and a pretest-posttest design does not control for extraneous variables.
-
Q #3: A nurse is caring for a patient who has been declared brain dead and is awaiting organ donation. Which of the following interventions is most important to preserve the viability of the organs?
A. Administering antibiotics to prevent infection.
B. Maintaining normal body temperature and blood pressure.
C. Providing emotional support to the family members.
D. Applying eye drops and ointment to prevent corneal drying.
Answer Explanation
The correct answer is choice B.
Maintaining normal body temperature and blood pressure.
Early identification and management of potential organ donors must take into consideration specific pathophysiologic changes for medical optimization 1.
The VIPPS (ventilation, infusion and pumping, pharmacological treatment, and specificities) strategy is a mnemonic method that brings together key aspects of the restoration of oxygen delivery to tissues during hemodynamic instability plus organ optimization strategies.
Choice A is incorrect because administering antibiotics to prevent infection is not the most important intervention to preserve organ viability.
Choice C is incorrect because providing emotional support to family members, while important, is not an intervention that directly affects organ viability.
Choice D is incorrect because applying eye drops and ointment to prevent corneal drying is not the most important intervention to preserve organ viability.
